These diseases, which claim 2 million lives each year, are likely to be the biggest emerging problem in 2025: Report

As we prepare to welcome the new year with hearts full of hope and prayers for good health, there are certain aspects we must pay close attention to. One such aspect is the lingering impact of the pandemic, which is still fresh in our minds.
Ever since we witnessed the grim impact of COVID pandemic, we have been asking ourselves “is there another pandemic threat on the horizon?”
“With COVID in retreat (thanks to highly effective vaccines), the three infectious diseases causing public health officials the greatest concern are malaria (a parasite), HIV (a virus) and tuberculosis (a bacterium). Between them, they kill around 2 million people each year,” a report published in The Conversation says and adds: There are also

priority pathogens

, particularly those that have developed resistance to common treatments like antibiotics and antivirals. Scientists must remain vigilant, constantly monitoring for emerging threats. While any pathogen could pose a risk, certain groups, such as influenza viruses, are more likely to cause rapid outbreaks.
“However, a recent study showed that a single mutation in the flu genome could make H5N1 adept at spreading from human to human, which could jump-start a pandemic. If this strain of bird flu makes that switch and can start transmitting between humans, governments must act quickly to control the spread. Centres for disease control around the world have drawn up

pandemic preparedness plans

for bird flu and other diseases that are on the horizon,” the report says.

What are the pathogens we need to be careful about in 2025?

Bird flu
One influenza virus currently raising significant concern is subtype H5N1, commonly known as “bird flu.” This virus is prevalent among wild and domestic birds, including poultry. Recently, it has also been reported in dairy cattle across several US states and in horses in Mongolia, heightening fears of a potential outbreak in 2025.

Malaria
Malaria remains a significant global health threat. The disease, caused by Plasmodium parasites transmitted through mosquito bites, continues to affect millions of people, primarily in sub-Saharan Africa. Despite significant advances in prevention and treatment, such as insecticide-treated nets and antimalarial drugs, challenges remain. Drug resistance is on the rise. In addition, climate change is expanding the habitats of malaria-carrying mosquitoes, making more regions vulnerable to outbreaks. Economic instability, limited healthcare access, and disruptions from global crises like the COVID-19 pandemic have also hindered malaria control efforts, leading to increased cases and deaths.

HIV
HIV remains a major global health concern. Despite advancements the virus still affects millions worldwide. Stigma, inadequate healthcare access, and drug resistance hinder progress in managing HIV. New infections continue to rise in some regions due to limited prevention programs, lack of awareness, and unsafe practices.
Tuberculosis (TB)
Tuberculosis (TB) can be a significant health threat, especially in low-income countries with limited access to healthcare. TB continues to cause millions of deaths annually. The rise of drug-resistant TB strains, such as multidrug-resistant (MDR) and extensively drug-resistant (XDR) TB, complicates treatment and control efforts. Factors like poor healthcare infrastructure, malnutrition, and HIV co-infection further exacerbate the problem.